The French forward arrives at Anfield on a six-year contract following Liverpool intensifying their search for an additional forward for Arne Slot's team.
The Reds are expected to pay Frankfurt a confirmed fee of £69 million upfront, along with £10 million in performance-related bonuses.
Ekitike attracted Premier League interest after scoring 22 goals and providing 12 assists across all competitions last season, while being included in the Bundesliga Team of the Season.
Newcastle were among the clubs interested in the 23-year-old and had a £70 million bid rejected by Frankfurt before withdrawing from negotiations.
Liverpool had contemplated pursuing Newcastle starAlexander Isak and expressed their readiness to pay £120 million for the Swedish international. However, they were informed he was not available for transfer and redirected their focus to Ekitike, finalizing the deal in time for the club's pre-season tour of Hong Kong and Japan.

Ekitike joined Frankfurt initially on loan from Paris Saint-Germain in February 2024, before the transfer was made permanent two months later.
On the international stage, he has yet to earn a senior cap for France, but has represented the Under-21 team five times.
He joins a revamped Liverpool squad gearing up to defend their Premier League title.Florian Wirtz, Jeremie Frimpong and Milos Kerkez have already been signed, while goalkeeperGiorgi Mamardashvili joined following an agreement last summer.